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All Outputs (48)

Homozygosity mapping of depressive disorder in a large family from Pakistan: Significant linkage on chromosome 6 and 9†‡ (2013)
Journal Article

A large family with a high prevalence of recurrent major depression and high average inbreeding coefficient was ascertained from rural Pakistan. Subjects were interviewed and diagnosed by a trained psychiatrist, 370 microsatellite markers were genoty... Read More about Homozygosity mapping of depressive disorder in a large family from Pakistan: Significant linkage on chromosome 6 and 9†‡.

Major depression in a large family in Pakistan: No relationship to inbreeding, economic status or rural living (2012)
Journal Article

Objective: To describe the relationships between depression and gender, socio-economic status, education, urban or rural living and coefficient of inbreeding in a well defined relatively homogeneous population. Design: Descriptive study. Place and Du... Read More about Major depression in a large family in Pakistan: No relationship to inbreeding, economic status or rural living.

Mutation in NSUN2, which Encodes an RNA Methyltransferase, Causes Autosomal-Recessive Intellectual Disability (2012)
Journal Article

Causes of autosomal-recessive intellectual disability (ID) have, until very recently, been under researched because of the high degree of genetic heterogeneity. However, now that genome-wide approaches can be applied to single multiplex consanguineou... Read More about Mutation in NSUN2, which Encodes an RNA Methyltransferase, Causes Autosomal-Recessive Intellectual Disability.

Urdu translation of the ICD-10 chapter V (F), Research Diagnostic Criteria (RDC): Process and principles of translation (2011)
Journal Article

Although there is some literature on translation and cultural adaptation of measurement scales, none is available on the translation of diagnostic guidelines, such as the International Classification of Diseases Tenth Edition (ICD-10). Our group tran... Read More about Urdu translation of the ICD-10 chapter V (F), Research Diagnostic Criteria (RDC): Process and principles of translation.

Preliminary Evaluation of Culturally Sensitive CBT for Depression in Pakistan: Findings from Developing Culturally-Sensitive CBT Project (DCCP) (2010)
Journal Article

Background: There is sufficient research evidence in favour of cognitive therapy in western world. However, only limited research has been carried out on its effectiveness in other countries. It is suggested that adaptations in content, format and de... Read More about Preliminary Evaluation of Culturally Sensitive CBT for Depression in Pakistan: Findings from Developing Culturally-Sensitive CBT Project (DCCP).

Psychologists Experience of Cognitive Behaviour Therapy in a Developing Country: a qualitative study from Pakistan (2010)
Journal Article

Background Psychological therapies especially Cognitive Behaviour Therapy (CBT) are used widely in the West to help patients with psychiatric problems. Cognitive Behaviour Therapy has an established evidence base for the treatment of different emotio... Read More about Psychologists Experience of Cognitive Behaviour Therapy in a Developing Country: a qualitative study from Pakistan.

Development of Southampton Adaptation Framework for CBT (SAF-CBT): A Framework for Adaptation of CBT in Non-Western Culture (2009)
Journal Article

Objective: To develop guidelines for adaptation of CBT in Pakistan. Design: Mixed methods ( both qualitative and quantitative). Place and Duration of Study: The studies were carried out in two cities in Pakistan, Rahim Yar Khan and Lahore, between Oc... Read More about Development of Southampton Adaptation Framework for CBT (SAF-CBT): A Framework for Adaptation of CBT in Non-Western Culture.

Identification of Mutations in TRAPPC9, which Encodes the NIK- and IKK-β-Binding Protein, in Nonsyndromic Autosomal-Recessive Mental Retardation (2009)
Journal Article

Mental retardation/intellectual disability is a devastating neurodevelopmental disorder with serious impact on affected individuals and their families, as well as on health and social services. It occurs with a prevalence of 2%, is an etiologically h... Read More about Identification of Mutations in TRAPPC9, which Encodes the NIK- and IKK-β-Binding Protein, in Nonsyndromic Autosomal-Recessive Mental Retardation.

INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse (2009)
Journal Article

The primary cilium is an antenna-like structure that protrudes from the cell surface of quiescent/differentiated cells and participates in extracellular signal processing. Here, we report that mice deficient for the lipid 5-phosphatase Inpp5e develop... Read More about INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse.

University students' views about compatibility of cognitive behaviour therapy (CBT) with their personal, social and religious values (a study from Pakistan) (2009)
Journal Article

Cognitive behaviour therapy (CBT) in its current form might not be applicable in non Western cultures. Differences between Western and non Western cultures have been reported widely. Psychotherapy was developed in the West and is underpinned by many... Read More about University students' views about compatibility of cognitive behaviour therapy (CBT) with their personal, social and religious values (a study from Pakistan).