All Outputs (2)

Photochemical Synthesis of Pyrazolines from Tetrazoles in Flow (2022)
Journal Article
Baumann, M., Burke, A., Spiccio, S., & Di Filippo, M. (2023). Photochemical Synthesis of Pyrazolines from Tetrazoles in Flow. SynOpen, 07(01), https://doi.org/10.1055/a-1995-1859

Pyrazolines and their pyrazole congeners are important heterocyclic building blocks with numerous applications in the fine chemical industries. However, traditional routes towards these entities are based on multistep syntheses generating substantial... Read More about Photochemical Synthesis of Pyrazolines from Tetrazoles in Flow.

Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate (2017)
Journal Article
Baumann, M., & Baxendale, I. R. (2017). Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate. Molbank, 2017(3), Article M951. https://doi.org/10.3390/m951

This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an i... Read More about Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate.