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Epidemiology of malaria in Gabon: A systematic review and meta-analysis from 1980 to 2023. (2024)
Journal Article
Sima-Biyang, Y. V., Ontoua, S. S., Longo-Pendy, N. M., Mbou-Boutambe, C., Makouloutou-Nzassi, P., Moussadji, C. K., …Boundenga, L. (2024). Epidemiology of malaria in Gabon: A systematic review and meta-analysis from 1980 to 2023. Journal of Infection and Public Health, 17(7), Article 102459. https://doi.org/10.1016/j.jiph.2024.05.047

The objective of this were conducted to elucidate spatiotemporal variations in malaria epidemiology in Gabon since 1980. For that, five databases, were used to collect and identify all studies published between 1980 and 2023 on malaria prevalence, an... Read More about Epidemiology of malaria in Gabon: A systematic review and meta-analysis from 1980 to 2023..

Investigation of caliciviruses and astroviruses in Gabonese rodents: A possible influence of national and international trade on the spread of enteric viruses. (2024)
Journal Article
Mbou-Boutambe, C., Mombo, I. M., Rougeron, V., Degrugillier, F., Gauthier, P., Makanga, B., …Boundenga, L. (2024). Investigation of caliciviruses and astroviruses in Gabonese rodents: A possible influence of national and international trade on the spread of enteric viruses. Infection, Genetics and Evolution, 122, Article 105607. https://doi.org/10.1016/j.meegid.2024.105607

Caliciviruses (Caliciviridae) and astroviruses (Astroviridae) are among the leading cause of non-bacterial foodborne disease and gastroenteritis in human. These non-enveloped RNA viruses infect a wide range of vertebrate species including rodents. Ro... Read More about Investigation of caliciviruses and astroviruses in Gabonese rodents: A possible influence of national and international trade on the spread of enteric viruses..

Evidence for circulation of Rift Valley fever virus in wildlife and domestic animals in a forest environment in Gabon, Central Africa. (2024)
Journal Article
Becquart, P., Bohou Kombila, L., Mebaley, T. N., Paupy, C., Garcia, D., Nesi, N., …N'Dilimabaka, N. (2024). Evidence for circulation of Rift Valley fever virus in wildlife and domestic animals in a forest environment in Gabon, Central Africa. PLoS Neglected Tropical Diseases, 18(3), Article e0011756. https://doi.org/10.1371/journal.pntd.0011756

Rift Valley fever (RVF) is a mosquito-borne viral zoonosis caused by the Rift Valley fever virus (RVFV) that can infect domestic and wild animals. Although the RVFV transmission cycle has been well documented across Africa in savanna ecosystems, litt... Read More about Evidence for circulation of Rift Valley fever virus in wildlife and domestic animals in a forest environment in Gabon, Central Africa..

Risk Factors Associated with Opportunistic Infections among People Living with HIV/AIDS and Receiving an Antiretroviral Therapy in Gabon, Central Africa. (2024)
Journal Article
Mouinga-Ondeme, A., Longo-Pendy, N. M., Moussadji Kinga, I. C., Ngoubangoye, B., Moussavou-Boundzanga, P., Boundenga, L., …Ngoungou, E. B. (2024). Risk Factors Associated with Opportunistic Infections among People Living with HIV/AIDS and Receiving an Antiretroviral Therapy in Gabon, Central Africa. Viruses, 16(1), Article 85. https://doi.org/10.3390/v16010085

The Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) is still one of the main causes of death in sub-Saharan Africa. Antiretroviral therapies (ARTs) have significantly improved the health conditions of people living with HIV... Read More about Risk Factors Associated with Opportunistic Infections among People Living with HIV/AIDS and Receiving an Antiretroviral Therapy in Gabon, Central Africa..

A cross-sectional study of malaria transmission in suggests the existence of a potential bridge vector susceptible of ensuring the transfer of simian malaria parasites to humans (2023)
Journal Article
Longo-Pendy, N., Boundenga, L., Makanga, B. K., Mbou-Boutambe, C., Bouafou, L., Akone-Ella, O., …Kengne, P. (2023). A cross-sectional study of malaria transmission in suggests the existence of a potential bridge vector susceptible of ensuring the transfer of simian malaria parasites to humans. Frontiers in Ecology and Evolution, 11, Article 1176687. https://doi.org/10.3389/fevo.2023.1176687

Introduction: Despite all the efforts made to control or even eliminate malaria, the disease continues to claim the highest number of victims of vector-borne pathogens in the world and Sub-Saharan countries bear the heaviest burden. The lack of knowl... Read More about A cross-sectional study of malaria transmission in suggests the existence of a potential bridge vector susceptible of ensuring the transfer of simian malaria parasites to humans.

Pharmaceutical activity of a synthetic heterocyclic (C15 H12 N5 OCl) compound on Entamoeba histolytica and Giardia lamblia (2023)
Journal Article
Obaid, H. M., Sale, S. S., & Boundenga, L. (2023). Pharmaceutical activity of a synthetic heterocyclic (C15 H12 N5 OCl) compound on Entamoeba histolytica and Giardia lamblia. Russian Journal of Infection and Immunity, 13(1), 119-126. https://doi.org/10.15789/2220-7619-pao-2024

Background.
Intestinal parasites are among the most important infectious agents with an impact on human health. Indeed, in the lack of an available treatment option, these parasites could constitute a real health problem in the population. In the p... Read More about Pharmaceutical activity of a synthetic heterocyclic (C15 H12 N5 OCl) compound on Entamoeba histolytica and Giardia lamblia.

Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa (2023)
Journal Article
Boundenga, L., Bignoumba, M., Dibakou, S., Mombo, L. E., Moukagni-Mussadji, C. J., Wora, D. M., …Onanga, R. (2023). Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa. Journal of Public Health in Africa, 14(3), https://doi.org/10.4081/jphia.2023.1865

Background. In Gabon, malaria remains a major public health problem. All malaria cases with axillary temperature ≥ 37.5°C with a parasites density ≥ 1200/μL are serious cases and must be treated as a medical emergency. Thus, early diagnosis is essent... Read More about Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa.

Gastrointestinal Polyparasitism in Bushmeat in Zadie Department in Northeast Gabon (2023)
Journal Article
Maganga, G. D., Makouloutou-Nzassi, P., Boundenga, L., Maganga Landjekpo, H. N., Bangueboussa, F., Ndong Mebaley, T., …Gbati, O. B. (2023). Gastrointestinal Polyparasitism in Bushmeat in Zadie Department in Northeast Gabon. Veterinary Sciences, 10(3), Article 229. https://doi.org/10.3390/vetsci10030229

Wildlife is an important source of infectious pathogens, including parasites. Intestinal parasites are among the parasites associated with outbreaks of foodborne disease. This article analyses gastrointestinal parasites in fecal and intestine samples... Read More about Gastrointestinal Polyparasitism in Bushmeat in Zadie Department in Northeast Gabon.

Molecular Identification of Trypanosome Diversity in Domestic Animals Reveals the Presence of Trypanosoma brucei gambiense in Historical Foci of Human African Trypanosomiasis in Gabon (2022)
Journal Article
Boundenga, L., Mombo, I. M., Augustin, M., Barthélémy, N., Nzassi, P. M., Moukodoum, N. D., …Prugnolle, F. (2022). Molecular Identification of Trypanosome Diversity in Domestic Animals Reveals the Presence of Trypanosoma brucei gambiense in Historical Foci of Human African Trypanosomiasis in Gabon. Pathogens, 11(9), https://doi.org/10.3390/pathogens11090992

Human African Trypanosomiasis (HAT) is an infectious disease caused by protozoan parasites belonging to the Trypanosoma genus. In sub-Saharan Africa, there is a significant threat as many people are at risk of infection. Despite this, HAT is classifi... Read More about Molecular Identification of Trypanosome Diversity in Domestic Animals Reveals the Presence of Trypanosoma brucei gambiense in Historical Foci of Human African Trypanosomiasis in Gabon.

Using haematophagous fly blood meals to study the diversity of blood‐borne pathogens infecting wild mammals (2022)
Journal Article
Mwakasungula, S., Rougeron, V., Arnathau, C., Boundenga, L., Miguel, E., Boissière, A., …Prugnolle, F. (2022). Using haematophagous fly blood meals to study the diversity of blood‐borne pathogens infecting wild mammals. Molecular Ecology Resources, 22(8), 2915-2927. https://doi.org/10.1111/1755-0998.13670

Many emerging infectious diseases originate from wild animals, so there is a profound need for surveillance and monitoring of their pathogens. However, the practical difficulty of sample acquisition from wild animals tends to limit the feasibility an... Read More about Using haematophagous fly blood meals to study the diversity of blood‐borne pathogens infecting wild mammals.

Human T-Lymphotropic virus type 1 and human immunodeficiency virus co-infection in rural Gabon (2022)
Journal Article
Mouinga-Ondémé, A., Boundenga, L., Koumba Koumba, I. P., Idam Mamimandjiami, A., Diané, A., Engone-Ondo, J. D., …Aghokeng Fobang, A. (2022). Human T-Lymphotropic virus type 1 and human immunodeficiency virus co-infection in rural Gabon. PLoS ONE, 17(7), https://doi.org/10.1371/journal.pone.0271320

Introduction Human T-cell lymphotrophic virus type-1 (HTLV-1) and human immunodeficiency virus (HIV-1) co-infection occur in many populations. People living with HIV-1 and infected with HTLV-1 seem more likely to progress rapidly towards AIDS. Both H... Read More about Human T-Lymphotropic virus type 1 and human immunodeficiency virus co-infection in rural Gabon.

Preliminary assessment of gastrointestinal parasites of the sun-tailed monkey (Allochrocebus solatus) in a semi-free-ranging colony (2022)
Journal Article
Dibakou, S., Ngoubangoye, B., Boundenga, L., Ntie, S., Moussadji, C., Tsoumbou, T., & Setchell, J. M. (2022). Preliminary assessment of gastrointestinal parasites of the sun-tailed monkey (Allochrocebus solatus) in a semi-free-ranging colony. Journal of Medical Primatology, 51(3), 127-133. https://doi.org/10.1111/jmp.12581

Background: The occurrence of gastrointestinal parasites in the sun-tailed monkey (Allochrocebus solatus) at the CIRMF primatology center is unknown. We, therefore, assessed the presence and richness (number of different parasite taxa) of gastrointes... Read More about Preliminary assessment of gastrointestinal parasites of the sun-tailed monkey (Allochrocebus solatus) in a semi-free-ranging colony.