All Outputs (3)

Spider venom neurotoxin based bioinsecticides: A novel bioactive for the control of the Asian citrus psyllid Diaphorina citri (Hemiptera) (2024)
Journal Article
Miranda, M. P., Fitches, E. C., Sukiran, N. A., Eduardo, W. I., Garcia, R. B., Jaciani, F. J., …Peña, L. (2024). Spider venom neurotoxin based bioinsecticides: A novel bioactive for the control of the Asian citrus psyllid Diaphorina citri (Hemiptera). Toxicon: An Interdisciplinary Journal on the Toxins Derived from Animals, Plants and Microorganisms, 239, Article 107616. https://doi.org/10.1016/j.toxicon.2024.107616

The Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Psyllidae), is a key vector of the phloem-limited bacteria Candidatus Liberibacter asiaticus (CLas) associated with huanglongbing (HLB), the most serious and currently... Read More about Spider venom neurotoxin based bioinsecticides: A novel bioactive for the control of the Asian citrus psyllid Diaphorina citri (Hemiptera).

Heterologous production of the insecticidal pea seed albumin PA1 protein by Pichia pastoris and protein engineering to potentiate aphicidal activity via fusion to snowdrop lectin Galanthus nivalis agglutinin; GNA) (2023)
Journal Article
De-Thier, J. S., Pyati, P., Bell, J., Readshaw, J. J., Brown, A. P., & Fitches, E. C. (2023). Heterologous production of the insecticidal pea seed albumin PA1 protein by Pichia pastoris and protein engineering to potentiate aphicidal activity via fusion to snowdrop lectin Galanthus nivalis agglutinin; GNA). Microbial Cell Factories, 22(1), Article 157. https://doi.org/10.1186/s12934-023-02176-1

Background
New bioinsecticides with novel modes of action are urgently needed to minimise the environmental and safety hazards associated with the use of synthetic chemical pesticides and to combat growing levels of pesticide resistance. The pea see... Read More about Heterologous production of the insecticidal pea seed albumin PA1 protein by Pichia pastoris and protein engineering to potentiate aphicidal activity via fusion to snowdrop lectin Galanthus nivalis agglutinin; GNA).

The insecticidal activity of recombinant nemertide toxin α-1 from Lineus longissimus towards pests and beneficial species (2021)
Journal Article
Bell, J., Sukiran, N. A., Walsh, S., & Fitches, E. C. (2021). The insecticidal activity of recombinant nemertide toxin α-1 from Lineus longissimus towards pests and beneficial species. Toxicon: An Interdisciplinary Journal on the Toxins Derived from Animals, Plants and Microorganisms, 197, 79-86. https://doi.org/10.1016/j.toxicon.2021.04.003

The nemertide toxins from the phylum Nemertea are a little researched family of neurotoxins with potential for development as biopesticides. Here we report the recombinant production of nemertide α-1 (α-1), a 65-residue inhibitor cystine knot (ICK) p... Read More about The insecticidal activity of recombinant nemertide toxin α-1 from Lineus longissimus towards pests and beneficial species.