All Outputs (4)

Impact of wavefront distortion and scattering on 2-photon microscopy in mammalian brain tissue. (2011)
Journal Article
Chaigneau, E., Wright, A. J., Poland, S. P., Girkin, J. M., & Silver, R. A. (2011). Impact of wavefront distortion and scattering on 2-photon microscopy in mammalian brain tissue. Optics Express, 19(23), 22755-22774. https://doi.org/10.1364/oe.19.022755

Two-photon (2P) microscopy is widely used in neuroscience, but the optical properties of brain tissue are poorly understood. We have investigated the effect of brain tissue on the 2P point spread function (PSF2P) by imaging fluorescent beads through... Read More about Impact of wavefront distortion and scattering on 2-photon microscopy in mammalian brain tissue..

Real-time optical gating for three-dimensional beating heart imaging (2011)
Journal Article
Taylor, J., Saunter, C., Love, G., Girkin, J., Henderson, D., & Chaudhry, B. (2011). Real-time optical gating for three-dimensional beating heart imaging. Journal of Biomedical Optics, 16(11), https://doi.org/10.1117/1.3652892

We demonstrate real-time microscope image gating to an arbitrary position in the cycle of the beating heart of a zebrafish embryo. We show how this can be used for high-precision prospective gating of fluorescence image slices of the moving heart. We... Read More about Real-time optical gating for three-dimensional beating heart imaging.

Improved method for kinetic studies in microreactors using flow manipulation and noninvasive Raman spectrometry. (2011)
Journal Article
Mozharov, S., Nordon, A., Littlejohn, D., Wiles, C., Watts, P., Dallin, P., & Girkin, J. (2011). Improved method for kinetic studies in microreactors using flow manipulation and noninvasive Raman spectrometry. Journal of the American Chemical Society, 133(10), 3601-3608. https://doi.org/10.1021/ja1102234

A novel method has been devised to derive kinetic information about reactions in microfluidic systems. Advantages have been demonstrated over conventional procedures for a Knoevenagel condensation reaction in terms of the time required to obtain the... Read More about Improved method for kinetic studies in microreactors using flow manipulation and noninvasive Raman spectrometry..

Multidepth, multiparticle tracking for active microrheology using a smart camera (2011)
Journal Article
Silburn, S. A., Saunter, C. D., Girkin, J. M., & Love, G. D. (2011). Multidepth, multiparticle tracking for active microrheology using a smart camera. Review of Scientific Instruments, 82(3), https://doi.org/10.1063/1.3567801

The quantitative measurement of particle motion in optical tweezers is an important tool in the study of microrheology and can be used in a variety of scientific and industrial applications. Active microheology, in which the response of optically tra... Read More about Multidepth, multiparticle tracking for active microrheology using a smart camera.