All Outputs (5)

Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development (2011)
Journal Article
Grellscheid, S., Dalgliesh, C., Storbeck, M., Best, A., Liu, Y., Jakubik, M., Mende, Y., Ehrmann, I., Curk, T., Rossbach, K., Bourgeois, C. F., Stévenin, J., Grellscheid, D., Jackson, M. S., Wirth, B., & Elliott, D. J. (2011). Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development. PLoS Genetics, 7(12), Article e1002390. https://doi.org/10.1371/journal.pgen.1002390

Alternative splicing amplifies the information content of the genome, creating multiple mRNA isoforms from single genes. The evolutionarily conserved splicing activator Tra2β (Sfrs10) is essential for mouse embryogenesis and implicated in spermatogen... Read More about Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development.

Molecular design of a splicing switch responsive to the RNA binding protein Tra2β (2011)
Journal Article
Grellscheid, S., Dalgliesh, C., Rozanska, A., Grellscheid, D., Bourgeois, C., Stévenin, J., & Elliott, D. (2011). Molecular design of a splicing switch responsive to the RNA binding protein Tra2β. Nucleic Acids Research, 39(18), 8092-8104. https://doi.org/10.1093/nar/gkr495

Tra2β regulates a number of splicing switches including activation of the human testis-specific exon HIPK3-T in the Homeodomain Interacting Protein Kinase 3 gene. By testing HIPK3-T exons of different intrinsic strengths, we found Tra2β most efficien... Read More about Molecular design of a splicing switch responsive to the RNA binding protein Tra2β.

General-purpose event generators for LHC Physics (2011)
Journal Article
Buckley, A., Butterworth, J., Gieseke, S., Grellscheid, D., Hoche, S., Hoeth, H., …Webber, B. (2011). General-purpose event generators for LHC Physics. Physics Reports, 504(5), 145-233. https://doi.org/10.1016/j.physrep.2011.03.005

We review the physics basis, main features and use of general-purpose Monte Carlo event generators for the simulation of proton–proton collisions at the Large Hadron Collider. Topics included are: the generation of hard scattering matrix elements for... Read More about General-purpose event generators for LHC Physics.

New Constraints on Gauge Mediation and Beyond from LHC SUSY Searches at 7 TeV (2011)
Journal Article
Dolan, M., Grellscheid, D., Jaeckel, J., Khoze, V., & Richardson, P. (2011). New Constraints on Gauge Mediation and Beyond from LHC SUSY Searches at 7 TeV. Journal of High Energy Physics, 2011(06), https://doi.org/10.1007/jhep06%282011%29095

The first results from the LHC on jets plus missing energy provide powerful new data to test SUSY models. Initial theoretical interpretations of these data have concentrated on gravity mediation, usually the CMSSM and its variations. In this paper we... Read More about New Constraints on Gauge Mediation and Beyond from LHC SUSY Searches at 7 TeV.

Herwig++ 2.5 Release Note (2011)
Journal Article
Gieseke, S., Grellscheid, D., Hamilton, K., Papaefstathiou, A., Platzer, S., Richardson, P., Röhr, C. A., Ruzicka, P., Siódmok, A., Suter,, . L., & Winn, D. (2011). Herwig++ 2.5 Release Note. arXiv,