All Outputs (3)

Genetic Variation in the Psychiatric Risk Gene CACNA1C Modulates Reversal Learning Across Species (2018)
Journal Article
Sykes, L., Haddon, J., Lancaster, T. M., Sykes, A., Azzouni, K., Ihssen, N., Moon, A. L., Lin, T.-C. E., Linden, D. E., Owen, M. J., O'Donovan, M. C., Humby, T., Wilkinson, L. S., Thomas, K. L., & Hall, J. (2019). Genetic Variation in the Psychiatric Risk Gene CACNA1C Modulates Reversal Learning Across Species. Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders, 45(5), 1024-1032. https://doi.org/10.1093/schbul/sby146

Genetic variation in CACNA1C, which encodes the alpha-1 subunit of Cav1.2 L-type voltage-gated calcium channels (VGCCs), has been strongly linked to risk for psychiatric disorders including schizophrenia and bipolar disorder. How genetic variation in... Read More about Genetic Variation in the Psychiatric Risk Gene CACNA1C Modulates Reversal Learning Across Species.

Structural and Functional Neuroimaging of Polygenic Risk for Schizophrenia: A Recall-by-Genotype–Based Approach (2018)
Journal Article
Lancaster, T. M., Dimitriadis, S. L., Tansey, K. E., Perry, G., Ihssen, N., Jones, D. K., …Linden, D. E. (2019). Structural and Functional Neuroimaging of Polygenic Risk for Schizophrenia: A Recall-by-Genotype–Based Approach. Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders, 45(2), 405-414. https://doi.org/10.1093/schbul/sby037

Risk profile scores (RPS) derived from genome-wide association studies (GWAS) explain a considerable amount of susceptibility for schizophrenia (SCZ). However, little is known about how common genetic risk factors for SCZ influence the structure and... Read More about Structural and Functional Neuroimaging of Polygenic Risk for Schizophrenia: A Recall-by-Genotype–Based Approach.

Preliminary evidence for genetic overlap between body mass index and striatal reward response (2018)
Journal Article
Lancaster, T. M., Ihssen, N., Brindley, L. M., & Linden, D. E. (2018). Preliminary evidence for genetic overlap between body mass index and striatal reward response. Translational Psychiatry, 8, Article 19. https://doi.org/10.1038/s41398-017-0068-4

The reward-processing network is implicated in the aetiology of obesity. Several lines of evidence suggest obesity-linked genetic risk loci (such as DRD2 and FTO) may influence individual variation in body mass index (BMI) through neuropsychological... Read More about Preliminary evidence for genetic overlap between body mass index and striatal reward response.