All Outputs (2)

Neuroprotective effects of ellorarxine in neuronal models of degeneration (2024)
Journal Article
Kouchmeshky, A., Whiting, A., & McCaffery, P. (2024). Neuroprotective effects of ellorarxine in neuronal models of degeneration. Frontiers in Neuroscience, 18, Article 1422294. https://doi.org/10.3389/fnins.2024.1422294

Introduction: Retinoic acid (RA) was first recognised to be important for the central nervous system (CNS) in its developmental regulatory role and, given this action, it has been proposed in the adult CNS to regulate plasticity and promote regenerat... Read More about Neuroprotective effects of ellorarxine in neuronal models of degeneration.

Evaluation of a Synthetic Retinoid, Ellorarxine, in the NSC-34 Cell Model of Motor Neuron Disease (2024)
Journal Article
Escudier, O., Zhang, Y., Whiting, A., & Chazot, P. (2024). Evaluation of a Synthetic Retinoid, Ellorarxine, in the NSC-34 Cell Model of Motor Neuron Disease. International Journal of Molecular Sciences, 25(18), Article 9764. https://doi.org/10.3390/ijms25189764

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease worldwide and is characterized by progressive muscle atrophy. There are currently two approved treatments, but they only relieve symptoms briefly and do not cure the disease.... Read More about Evaluation of a Synthetic Retinoid, Ellorarxine, in the NSC-34 Cell Model of Motor Neuron Disease.