Opening of the Outer Membrane Protein Channel in Tripartite Efflux Pumps Is Induced by Interaction with the Membrane Fusion Partner

Janganan, T.K.; Zhang, L.; Bavro, V.N.; Matak-Vinkovic, D.; Barrera, N.P.; Burton, M.F.; Steel, P.G.; Robinson, C.V.; Borges-Walmsley, M.I.; Walmsley, A.R.

doi:10.1074/jbc.m110.187658

All Outputs (2)

Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3 (2011)
Journal Article
Janganan, T., Bavro, V., Zhang, L., Matak-Vinkovic, D., Barrera, N., Venien-Bryan, C., …Walmsley, A. (2011). Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3. Journal of Biological Chemistry, 286(30), 26900-26912. https://doi.org/10.1074/jbc.m111.246595

The multiple transferable resistance (mTR) pump from Neisseria gonorrhoeae MtrCDE multidrug pump is assembled from the inner and outer membrane proteins MtrD and MtrE and the periplasmic membrane fusion protein MtrC. Previously we established that wh... Read More about Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3.

Opening of the Outer Membrane Protein Channel in Tripartite Efflux Pumps Is Induced by Interaction with the Membrane Fusion Partner (2011)
Journal Article
Janganan, T., Zhang, L., Bavro, V., Matak-Vinkovic, D., Barrera, N., Burton, M., …Walmsley, A. (2011). Opening of the Outer Membrane Protein Channel in Tripartite Efflux Pumps Is Induced by Interaction with the Membrane Fusion Partner. Journal of Biological Chemistry, 286(7), 5484-5493. https://doi.org/10.1074/jbc.m110.187658

The multiple transferable resistance (MTR) pump, from Neisseria gonorrhoeae, is typical of the specialized machinery used to translocate drugs across the inner and outer membranes of Gram-negative bacteria. It consists of a tripartite complex compose... Read More about Opening of the Outer Membrane Protein Channel in Tripartite Efflux Pumps Is Induced by Interaction with the Membrane Fusion Partner.