Seasonality, climatic unpredictability, food deprivation and polycystic ovary syndrome
Shaw, L.; Elton, S.
Professor Sarah Elton firstname.lastname@example.org
Stein and Leventhal’s finding of polycystic ovaries, which they eponymously described as part of a circumscribed clinical syndrome , has evolved to become a nebulous entity with polycystic ovaries as a prominent component. Biochemical aspects, both endocrine and non-endocrine, have become part of a wider “polycystic ovary syndrome” (PCOS), recognised as a very common cause of anovulatory infertility [2 – 4]. Whilst the original Stein-Leventhal Syndrome described multiple ovarian cysts, obesity, hirsutism, menstrual abnormalities and amenorrhoea, symptoms of PCOS also include acne and androgenic alopecia. Obesity, when it occurs, tends to include centrally-distributed adipose tissue. These features, singly or together, are not evident in all affected women . Despite this, most show a degree of insulin resistance . PCOS is thus a complex endocrine disorder, for which the diagnosis is not always straightforward [6, 7]. However, many practitioners now agree that it can be defined on the basis of at least two of the following features in combination: presence of polycystic ovaries on ultrasound examination; oligo-/anovulation; clinical or biochemical evidence of androgen excess .
Shaw, L., & Elton, S. (2008). Seasonality, climatic unpredictability, food deprivation and polycystic ovary syndrome. In S. Elton, & P. O’Higgins (Eds.), Medicine and evolution : current applications, future prospects (77-97). CRC Press. https://doi.org/10.1201/9781420051377.ch5
|Deposit Date||May 20, 2013|
|Publicly Available Date||Mar 1, 2016|
|Series Title||Society for the study of human biology series|
|Book Title||Medicine and evolution : current applications, future prospects.|
Accepted Book Chapter
This is an Accepted Manuscript of a book chapter published by Routledge in Medicine and evolution : current applications, future prospects on 2 June 2008 available online: http://www.routledge.com/9781420051346
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