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EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

Butler, Stephen J.; Lamarque, Laurent; Pal, Robert; Parker, David

EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging Thumbnail


Authors

Stephen J. Butler

Laurent Lamarque



Abstract

Nine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo. Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

Citation

Butler, S. J., Lamarque, L., Pal, R., & Parker, D. (2014). EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging. Chemical Science, 2014(5), 1750-1756. https://doi.org/10.1039/c3sc53056f

Journal Article Type Article
Acceptance Date Dec 11, 2013
Online Publication Date Jan 27, 2014
Publication Date May 1, 2014
Deposit Date Jun 18, 2014
Publicly Available Date Dec 11, 2014
Journal Chemical Science
Print ISSN 2041-6520
Electronic ISSN 2041-6539
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
Volume 2014
Issue 5
Pages 1750-1756
DOI https://doi.org/10.1039/c3sc53056f

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