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Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes

Carr, Rachel; Puckrin, Robert; McMahon, Brian K.; Pal, Robert; Parker, David; Pålsson, Lars-Olof

Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes Thumbnail


Authors

Rachel Carr

Robert Puckrin

Brian K. McMahon



Abstract

A circularly polarized luminescence (CPL) spectrometer has been built and used to study the binding interaction of lactate and four different proteins with racemic EuIII and TbIII complexes in aqueous solution. Lactate binding gives rise to strong induced CPL spectra, and the observed emission dissymmetry factors vary linearly with enantiomeric composition. Particularly strong induced TbIII CPL also characterizes the binding interaction of alpha-1-acid glycoprotein with a dissociation constant, Kd, of 2.5 μM.

Citation

Carr, R., Puckrin, R., McMahon, B. K., Pal, R., Parker, D., & Pålsson, L. (2014). Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes. Methods and Applications in Fluorescence, 2(2), Article 024007. https://doi.org/10.1088/2050-6120/2/2/024007

Journal Article Type Article
Acceptance Date Dec 18, 2013
Online Publication Date Apr 9, 2014
Publication Date Jun 1, 2014
Deposit Date Jun 19, 2014
Publicly Available Date Dec 9, 2014
Journal Methods and Applications in Fluorescence
Publisher IOP Publishing
Peer Reviewed Peer Reviewed
Volume 2
Issue 2
Article Number 024007
DOI https://doi.org/10.1088/2050-6120/2/2/024007

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Copyright Statement
Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.








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