Triply Threaded Rotaxanes
Danon, J.J.; Leigh, D.A.; McGonigal, P.R.; Ward, J.W.; Wu, J.
Dr Paul Mcgonigal email@example.com
Rotaxanes featuring three axles threaded through a single ring have been prepared through active metal template synthesis. Nickel-catalyzed sp3-sp3 homocouplings of alkyl bromide ‘half threads’ through 37- and 38-membered 2,2':6',2"-terpyridyl macrocycles generates triply-threaded rotaxanes in up to 11 % yield. An analogous 39-membered macrocycle produced no rotaxane products under similar conditions. The constitutions of the rotaxanes were determined by NMR spectroscopy and mass spectrometry. Doubly-threaded rotaxanes were also obtained from the reactions but no rotaxanes were isolated, suggesting that upon demetallation the axle of a singly-threaded rotaxane can slip through a macrocycle that is sufficiently large to accommodate three threads.
Danon, J., Leigh, D., McGonigal, P., Ward, J., & Wu, J. (2016). Triply Threaded Rotaxanes. Journal of the American Chemical Society, 138(38), 12643-12647. https://doi.org/10.1021/jacs.6b07733
|Journal Article Type||Article|
|Acceptance Date||Aug 29, 2016|
|Online Publication Date||Aug 29, 2016|
|Publication Date||Sep 28, 2016|
|Deposit Date||Sep 4, 2016|
|Publicly Available Date||Sep 5, 2016|
|Journal||Journal of the American Chemical Society|
|Publisher||American Chemical Society|
|Peer Reviewed||Peer Reviewed|
Accepted Journal Article
ACS AuthorChoice - This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Published Journal Article
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