Synthesis and Functionalization of Azetidine‐Containing Small Macrocyclic Peptides
(2024)
Journal Article
Saunders, G. J., Spring, S. A., Jayawant, E., Wilkening, I., Roesner, S., Clarkson, G. J., Dixon, A. M., Notman, R., & Shipman, M. (2024). Synthesis and Functionalization of Azetidine‐Containing Small Macrocyclic Peptides. Chemistry - A European Journal, 30(28), Article e202400308. https://doi.org/10.1002/chem.202400308
Cyclic peptides are increasingly important structures in drugs but their development can be impeded by difficulties associated with their synthesis. Here, we introduce the 3-aminoazetidine (3-AAz) subunit as a new turn-inducing element for the effici... Read More about Synthesis and Functionalization of Azetidine‐Containing Small Macrocyclic Peptides.